In view of the problem that the research on the evaluation method of main bearing deformation coordination characteristic is relatively scarce and the calculation of existing evaluation index is complicated, the maximum radial deformation of main bearing bush for single main bearing was proposed as the evaluation index of main bearing deformation coordination characteristic, the numerical calculation method of maximum radial deformation was studied and the correctness of evaluation method and calculation method was verified by experiments. Based on the analysis on sensitivity of design parameters to the maximum radial deformation of main bearing bush, the influence laws of typical design parameters on the maximum radial deformation were discussed. The results show that the method of evaluating the main bearing deformation coordination characteristic is feasible by the maximum radial deformation of main bearing bush and the error between the calculation result and the test measurement data is within 7%. When the load of main bearing remains constant, the maximum radial deformation decreases gradually and finally becomes constant with the increase of bolt preload. For the current engine type, the increase of interference will cause the maximum radial deformation of main bearing to gradually decrease, but the redundant interference load may cause a slight increase in the maximum radial deformation when the interference is beyond 0.17 mm. With the increase of the side clearance between the body and main bearing cover, the maximum radial deformation of main bearing bush shows a linearly increasing trend.